Senior Director, Precision Medicine Therapeutic Area Lead - Oncology

Company: Amgen
Location: Washington
Posted on: June 24, 2025

Job Description:

Join Amgens Mission of Serving Patients At Amgen, if you feel like youre part of something bigger, its because you are. Our shared missionto serve patients living with serious illnessesdrives all that we do. Since 1980, weve helped pioneer the world of biotech in our fight against the worlds toughest diseases. With our focus on four therapeutic areas Oncology, Inflammation, General Medicine, and Rare Disease we reach millions of patients each year. As a member of the Amgen team, youll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Senior Director Precision Medicine Therapeutic Area Lead, Oncology Live What you will do Lets do this. Lets change the world. In this vital role you will act in conjunction with the Oncology Therapeutic Area head to advance the development and execution of Precision Medicine objectives. Lead multiple cross-functional teams to develop and execute translational and precision medicine strategies to support above-asset development across the pipeline. Additionally, partner with cross functional Therapeutic Area leads across Research & Development to guide the development of translational, reverse translational, and precision medicine strategies. Serve as thought partner and influencer to the Precision Medicine TA Head for the development and execution of strategies for translation, reverse translation, and precision medicine to deepen mechanistic insights, define indications/combinations based on understanding of disease & patient endotypes, enhance success, and overall value of the portfolio within the therapeutic area. Serve as the strategic integrator of various stakeholder inputs and multiple lines of evidence for the development of translational medicine and precision medicine strategies across multiple assets in the oncology pipeline with shared objectives, such as assets within an indication franchise, or multiple assets within a modality. Set strategic vision to enhance the value of the oncology pipeline through clinical biomarker target identification, indication selection, early indication of biological activity and patient stratification/selection including reverse translation strategies capable of informing across-asset learnings. Mentor and guide precision medicine scientists and junior precision medicine leads within the therapeutic area on phase appropriate exploration of precision medicine considerations to inform asset development strategic options. Lead multiple cross-functional teams in the development and execution of phase appropriate, integrated, biomarker and human data plans, to support translational pharmacology and inform patient selection strategies. Serve as the key liaison between research and development by providing clinical translational considerations (proof of target engagement, dose selection, patient selection) to inform discovery asset development as well as enabling reverse translational strategies (to gain mechanistic insights related to patient stratification, response/resistance) for assets in clinical phase. Provide precision medicine considerations to shape disease area strategies (disease endotypes, indications, and combinatorial approaches). Provide subject matter expertise to inform registrational and access and use evidence generation plans. In partnership with the Precision Medicine Therapeutic Area Head, help to identify and implement emerging technologies including AI into translational and biomarker development. Represent Precision Medicine as a key collaborator and thought partner with external collaborators and lead initiatives capable of informing the pipeline holistically. Win What we expect of you We are all different, yet we all use our unique contributions to serve patients. The dynamic professional we seek is a leader with these qualifications. Basic Qualifications: Doctorate degree and 5 years of relevant industry or academic translational research experience Or Masters degree and 8 years of relevant experience OR Bachelors degree and 10 years of relevant experience Preferred Qualifications: MD & PhD with 8 years industry & academic experience Deep scientific and analytical expertise in integrating multiple data sources e.g. omic, clinical, Real world evidence (RWE) to inform precision medicine approaches Strong professional network with external Key Opinion Leaders, academic institutions, and industry partners Experience in translational research and/or advancing clinical candidates Knowledge of Good Clinical Practices (GCP) and applicable regulatory requirements for biomarker and diagnostic development Proven ability to lead, manage, and motivate others in a complex, multi-functional matrix environment Exceptional leadership and team management skills What you can expect of us As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, well support your journey every step of the way. The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan Stock-based long-term incentives Award-winning time-off plans Flexible work models, including remote and hybrid work arrangements, where possible Apply now and make a lasting impact with the Amgen team. careers.amgen.com In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information. Application deadline Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease. Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Keywords: Amgen, Silver Spring , Senior Director, Precision Medicine Therapeutic Area Lead - Oncology, Healthcare , Washington, Maryland