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Software Modeling Specialist

Company: Brillient Corporation
Location: Silver Spring
Posted on: June 23, 2022

Job Description:

Brillient Corporation is seeking a Software Modeling Specialist to support modeling and simulation for advanced pharmaceutical manufacturing.Qualifications: --- Requires a bachelor's degree or higher in a science or engineering discipline (e.g. chemical/mechanical engineering) --- Four years plus of experience in applying modeling and simulation approaches to address scientific questions. --- Industrial or government experience applying modeling and simulation for processes and/or physical systems Characteristics: Modeling and Simulation-related experience demonstrating EACH of the following competencies. --- Knowledge of mechanistic modeling approaches that can be applied to pharmaceutical manufacturing including unit operations that involve particles and/or flowing powders for example integrated process models (i.e. flowsheet models), population balance models, Multiphysics (e.g. reactions kinetics and transport phenomenon), computational fluid dynamics, and/or discrete element modeling. --- Knowledge of machine learning and multivariate modeling approaches and data processing methods that can be applied to large data sets for example deep learning, principal component analysis, random forest etc. --- Knowledge and hands on experience with a range of modeling and simulation software platforms for example MATLAB, Simulink, gPROMS, Unscrambler, Umetrics, Python SciPy Stack, Mathematica, COMSOL, Fluent, and/or EDEM and willingness to learn platforms as needed --- Knowledge of parallel computation and executing codes on CPU clusters --- Knowledge of numerical methods for solving systems of ordinary and partial differential equations --- Knowledge of applying sensitivity analysis to evaluate modeling results --- Knowledge of modeling and simulation verification and validation practices. --- Attention to Detail - being thorough when planning, developing, and carrying out vital tasks in supporting research projects including model documentation. --- Customer Service - assisting others in the resolution of issues when developing models or interpreting modeling and simulation results. --- Collaboration - willing to participate in interdisciplinary projects working with members and managers, on product quality research projects and initiatives. --- Written Communication - expressing highly technical information (for example, ideas or facts) to individuals or groups effectively, taking into account the audience and nature of the information including scientific publications. --- Oral Communication - expressing highly technical information (for example, ideas or facts) to individuals or groups effectively, taking into account the audience and nature of the information. --- Problem Solving - conducting extensive investigation and analysis to determine the nature and scope of problems and devise solutions. --- Working knowledge of pharmaceutical development and manufacturing, a plus. Activities: --- Collaborates with DPQR staff to identify appropriate modeling and simulation methods based on expertise to advance product quality research goals including writing research proposals and protocols --- Collaborates with DPQR staff to identify the required experimental data for model development and validation. --- Develops and validates models to predict manufacturing process performance and/or product quality attributes --- Documents and communicates research results generated from modeling and simulation studies including writing technical reports, and scientific papers and delivering oral and poster presentations --- Works with DPQR management to coordinate activities for the modeling and simulation group within DPQR --- Works with DPQR management to establish collaborations with other modeling and simulation groups within the FDA --- Works with DPQR management to establish collaborations with external stakeholders on advancing the utilization of modeling and simulation in pharmaceutical development and manufacturing --- Develops training material and courses on modeling and simulation applied to pharmaceutical development and manufacturing --- Develops white papers on emerging topics in modeling and simulation for pharmaceutical development and manufacturing --- Manages scientific computing workstations for DPQR. --- Routinely updates management on the status and progress of the modeling and simulation research projects --- Acts as a modeling and simulation subject matter expert for other DPQR researchers

Keywords: Brillient Corporation, Silver Spring , Software Modeling Specialist, IT / Software / Systems , Silver Spring, Maryland

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